Paediatric & end of life consideration Flashcards

Divulges ethical consideration surrounding EOL and practical concerns of implanting systems in the paediatric/growing patient. Currently weighted 1% in the CCDS exam. (50 cards)

1
Q

True or False:

1 in 5 palliative care patients will experience tachyarrhythmias in the last weeks of their life.

A

True

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2
Q

True or False:

In lieu of programming, ICD shock therapy can be terminated by placing a magnet over the device.

A

True

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3
Q

True or False:

End of life issues should be discussed at the time of implant.

A

True

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4
Q

True or False:

The following statement is a class I indication for end of life ICD consideration.

‘Patients with refractory HF symptoms, refractory sustained VA, or nearing the end of life from other illness, clinicians should discuss ICD shock deactivation and consider the patients’ goals and preferences’.

A

True

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5
Q

True or False:

The following statement is a class I indication for end of life ICD consideration.

‘ICD implantation or replacement, and during advance care planning, patients should be informed that their ICD shock therapy can be deactivated at any time if it is consistent with their goals and preferences’.

A

True

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6
Q

True or False:

Cardiac pacemakers are usually placed in the subpectoral region for paediatrics.

A

False

Typically placed in the abdomen. Abdominal fat helps protect the pacemaker during falls, knocks and bumps that are part and parcel of childhood activity. Also less likely for twiddlers syndrome.

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7
Q

True or False:

Most infants <15kg receive endocardial leads.

A

False

Most receive epicardial leads as they’re easier to remove. Remember it’s likely the patient will have multiple revisions over their 60+ year lifetime.

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8
Q

True or False:

Paediatric pacing is mainly performed in the setting of SND.

A

False

It’s mainly performed in the setting of congenital or post-surgical complete heart block and less frequently in some surgical patients with sinus node dysfunction.

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9
Q

Epicardial leads in children are associated with

  1. Higher chronic stimulation threshold
  2. Higher lead failures and fractures
  3. Early depletion of battery life

Despite this, list the two reasons why these leads are used.

A
  1. Preserves venous access for later in life
  2. Easier to remove leads
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10
Q

True or False:

LV apical > RV apical as an epicardial pacing site for paediatrics.

A

True

Less dyssynchrony, better haemodynamics, less progression to HF.

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11
Q

True or False:

Paediatric venous obstruction post PPM lead implantation is related to the ratio of cross-sectional lead area to the body surface area at implantation.

A

True

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12
Q

Why is it wise to always perform a venography in paediatric patients?

A

Large proportion of implant cases will present with congenital defects.

Thus venography will highlight potentially complex anatomy.

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13
Q

List 3 paediatric cardiac anatomy abnormalities which increase implant difficulty.

A
  1. Structural heart defects (TOF etc)
  2. surgical repairs (Fontan, Mustard, Senning)
  3. Synthetic septal patches (PFO closure)
  4. Atrial baffles
  5. Conduits
  6. Absence of appendages
  7. Obstructed venous channels
  8. Persistent left superior vena cava
  9. Extensive surgical fibrosis
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14
Q

True or False:

Endocardial pacing is not an option in patients with single ventricles.

A

True

Access is eliminated from the systemic veins after the extracardiac conduit Fontan procedure.

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15
Q

True or False:

AV synchrony can add up to 15% to the paediatric cardiac output.

A

True

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16
Q

True or False:

Paediatrics have lower resting and peak heart rates than do adults.

A

False

Typically much higher than adults.

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17
Q

True or False:

Resting HR between 120-150bpm and peak rates >200bpm are not uncommon in paediatric patients.

A

True

Majority of PPMs can pace at rates up to 180bpm.

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18
Q

True or False:

Mismatch between peak HR and the generators ability to track this HR is of no concern in paediatrics.

A

False

Limits to MTR can result in reduced exercise tolerance, pVO2 and anaerobic threshold.

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19
Q

True or False:

Higher heart rates can have a negative effect on battery longevity.

A

True

More stimulation = faster battery depletion.

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20
Q

True or False:

Dual chamber pacemakers are generally reserved for patients >25Kg.

A

True

Due to size constraints a single chamber PPM will likely be used in smaller patients.

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21
Q

List the 3 main implant approaches for abdominal pacemakers.

A
  1. Sternotomy
  2. Thoracotomy
  3. Subxiphoid approach
22
Q

Which lead type is most likely to fail in paediatric patients?

  1. Conventional epicardial
  2. Steroid-eluting epicardial
  3. Steroid-eluting endocardial
  4. Conventional endocardial
A

Conventional epicardial leads.

No significant differences observed between the other 3 types.

23
Q

Why are active fixation leads preferable to passive fixation in paediatrics.

A

Easier to remove / revise.

High likelihood of revision as ~50% of leads will have failed by the 15yr mark.

24
Q

What is an atrial loop and why is it used when implanting paediatric endocardial ventricular leads?

A

Employing extra redundancy of the ventricular lead such that it forms a loop in the atrium.

This is to ensure better long term outcomes as the redundant slack will be used as the patient grows.

25
# True or False: Paediatric patients comprise \<1% of all PPM implants.
True ## Footnote *Indeed paediatric implant centres may only implant circa 10 systems per year.*
26
Describe what is meant by antibody positive vs. antibody negative for paediatric AVB.
* Antibody positive - Fetus develops AVB respondent to maternal antibodies / single stranded RNA crossing placenta and damaging conduction system. * Antibody negative - Develops later in life, AVB is more likely to be a progressive disease.
27
# True or False: Most common cause of AVB in congenital patients is respondent to damage from cardiac surgery.
True
28
# True or False: Paediatric incidence of AVB post surgery is \<2%.
True
29
# True or False: Typically paediatric patients with transient AVB will recover \<5 days.
False ## Footnote *If truly transient, patient will most likely recover within 10 days. After 10 days PPM insertion is likely treatment.*
30
# True or False: After \<7yrs of paediatric pacing, the following may be observed with epicardial implants. 1. ~13% partial venous occlusion 2. ~12% complete venous occlusion
False - these statistics are true of transvenous implants. Epicardial does not use venous access. ## Footnote *Bar-Cohen Y, Berul CI, Alexander ME, et al. Age, size, and lead factors alone do not predict venous obstruction in children and young adults with transvenous lead systems. J Cardiovasc Electrophysiol 2006.*
31
# True or False: Venous stenosis is always asymptomatic.
False ## Footnote *May present with venous congestion and swelling of the ipsilateral arm.*
32
# True or False: Paed endocardial systems have similar complications as adults, however the incidence is much lower.
False - incidence of complication in paediatrics is far higher. ## Footnote *Smaller size, more complex anatomy, fewer numbers, less experienced operators, more active lifestyle are all recognised contributors.*
33
# True or False: VVIR is the most common pacing mode in small children.
True ## Footnote *Children tolerate AV dyssynchrony better than adults and there's a preference to implant the least amount of hardware possible early in a child's life. Thus single chamber devices are standard.*
34
# True or False: Unpaced postoperative heart block carries a high mortality in paediatric patients.
True
35
Why should RVp should be minimised in paediatrics and how can it be achieved in SR systems?
Higher rates = More RVp over time. This is potentially detrimental as per MOST study findings. ## Footnote *Higher pacing % could increase risk of pacemaker syndrome and ventricular dysfunction. Thus program a lower HR and/or remove rate response function to encourage intrinsic conduction. Important to balance HR and respondent exercise tolerance with Vp%.*
36
List 3 reasons why CRT outcomes in paediatrics poor.
1. Paeds rarely present with LBBB and QRS \>150ms, which are markers of CRT success 2. CRT in adults is mainly ischemic based, in paeds its congenital or progressive cardiomyopathies 3. CRT isn't shown to benefit the failing RV, which is the most likely ventricle to fail in congenital scenarios
37
# True or False: Paediatric patients most likely to benefit from CRT are those with impaired LV function who are being paced from the RV (Thus presenting with LBBB morphology on ECG).
True
38
# Yes / No Can patients/guardians request discontinuation of tachy/brady therapy, even when not terminally ill?
Yes. ## Footnote *It is unethical to provide any treatment against a persons will.*
39
# True or False: All patients are asked about their wishes to cease device therapy at the time of implantation.
False ## Footnote *Only a small minority of patients are asked this question, when in fact all patients should be asked to ensure appropriate action is taken should the need arise.*
40
What should be ascertained when any request to end critical treatment is requested.
Cognitive competence and the ability to comprehend the consequences of changing device settings. ## Footnote *E.g. The difference between ending tachycardia therapy and/or pacing therapy in a dependent patient.*
41
# True or False: Withdrawal of Tach/Brady therapy is not akin to withdrawal of mechanical ventilators, haemodialysis or other life support machines and should never be performed.
False
42
# True or False: Withdrawal of Tach/Brady therapy is likened to assisted dying, analogous to voluntary euthanasia.
False
43
# True or False: A person's underlying condition is deemed the cause of death following treatment withdrawal.
True
44
# True or False: It is unethical to withdraw treatment that becomes part of the patient's self - I.e. organ transplant.
True ## Footnote *This does not apply cardiac devices.*
45
# True or False: From an ethical and legal standpoint, the following statement is true. 'Refusing cardiac device implant and withdrawal of cardiac device therapy are one and the same'.
True
46
What should be done if personal and professional opinions differ between clinician and patient with respect to withdrawal of therapy?
HRS guidelines state clinicians are obligated to arrange for alternative provision of care in cases of conscientious objection that cannot be resolved.
47
# True or False: Withdrawing bradycardia support is unlikely to result in instantaneous death but rather symptoms respondent to inadequate cardiac output like dizziness and syncope.
True
48
# True or False: In patients with a do not resuscitate order in force, ICD deactivation should be seriously considered.
True
49
# True or False: An active pacemaker will not affect the timing or circumstances of death as a patient typically becomes acidotic before cardiac arrest, rendering the pacemaker ineffective.
True
50
# True or False: Cardiac device deactivation is an extension of patients' self-determination regarding their own treatment.
True