Part 2: Physics & Equipment Flashcards

Apply principles of physics and measurement to anaesthesia, including pressure, flow, gas laws, vaporizers, electrical safety, and monitoring. (227 cards)

1
Q

How do capacitors behave differently for AC vs DC?

A

Capacitors block DC after an initial charge because they can’t sustain constant current, but they allow AC to pass through by continuously charging and discharging as the voltage changes.

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2
Q

List some sources of inaccuracy in a LiDCO cardiac monitor.

A
  • First trimester of pregnancy
  • Weight <40kg
  • Aortic regurgitation
  • Intra-aortic balloon pump
  • Therapeutic lithium administration
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3
Q

What proportion of total basal heat expenditure is used for humidifying and warming inspired dry gas?

A

0.15

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4
Q

What is a non-linearity error in measurement devices?

A

Occurs when the response of the device to changes in input is not a straight line.

This type of error can lead to inaccuracies in measurements at different points and is best corrected using multi-point calibration to align the device’s output with the actual values across its entire range.

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5
Q

What is the difference between low-level and high-level decontamination?

A

LOW LEVEL: Kills most bacteria (not TB), some fungi & viruses.
AGENTS: alcohol, chlorhexidine

HIGH LEVEL: Kills all bacteria (incl. TB), most fungi & viruses — can sterilise with time.
AGENTS: aldehydes, peracetic acid, chlorine dioxide

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6
Q

What result does an overdamped arterial line produce?

A
  • Low systolic
  • High diastolic
  • Normal MAP
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7
Q

What result does an underdamped arterial line produce?

A
  • High systolic
  • Low diastolic
  • Normal MAP
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8
Q

What is the sampling flow rate of a side-stream gas analyser?

A

Up to 200 mL/min

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9
Q

Which measure in ultrasound imaging is most useful for determining the likelihood of thermal injury from the apparatus?

A

Spatial peak temporal average intensity

(SPTA intensity)

Takes into account the highest intensity within the ultrasound beam over time and is most directly associated with the amount of energy absorbed by tissues, thus representing the most significant factor in minimising the risk of thermal injury.

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10
Q

What is the difference between unipolar and bipolar pacing on a pacemaker?

A
  • Unipolar pacing uses one electrode inside the heart and the pacemaker’s metal casing as the return, creating a larger electrical field and a bigger pacing spike on the ECG.
  • Bipolar pacing uses two closely spaced electrodes on the lead itself, confining the circuit locally and producing a smaller, sharper pacing spike.
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11
Q

Define density in the context of gases and how it changes with temperature.

A

Mass per unit volume of a gas

Increasing temperature decreases density (because the same mass of gas occupies a greater volume).

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12
Q

State the equation for kinetic energy.

A

KE = 1/2(mv^2)

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13
Q

List some metals that are ferromagnetic.

A
  • Cobalt
  • Iron
  • Gadolinium
  • Neodymium
  • Nickel
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14
Q

Which gases behave most like an ideal gas?

A

Inert gases like helium, argon, neon, and xenon.

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15
Q

What is an ideal gas?

A

Hypothetical gas whose

  • particles occupy NO VOLUME
  • experience NO INTERMOLECULAR FORCES
  • collisions are PERFECTLY ELASTIC and they obey the ideal gas law under all conditions
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16
Q

What explains the difference in appearance of different tissues in an MRI scan?

A
  • Chemical shift variation
  • Small differences in resonant frequency of hydrogen ions caused by their surrounding environment.
  • This changes how hydrogen nuclei respond to magnetic field and radiofrequency pulses.
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17
Q

Describe the appearance of an entonox cylinder.

A
  • Body that is usually blue (sometimes white) with blue and white shoulders.
  • Full cylinder pressure is 13700 KPa (137 bar).
  • A two-stage pressure regulator is attached to the cylinder to enable safe operational use.
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18
Q

What frequencies are used in diagnostic medical ultrasound?

A

2-15 MHz

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19
Q

Which piezoelectric material is used in ultrasound transducers?

A

Lead zirconate titanate

(PZT)

NOTE: The thickness of the material determines the frequency.

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20
Q

How does soda lime remove carbon dioxide?

A

CO2 reacts with water to form carbonic acid.

Carbonic acid reacts with calcium hydroxide to produce calcium carbonate, water and heat.

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21
Q

How is Fourier analysis useful for arterial line traces?

A

Decomposes arterial pressure waveforms into sinusoidal components allowing for a detailed examination of the waveform’s frequency content.

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22
Q

State the equation that links charge to capacitance.

A

V = Q/C

Potential difference across the capacitor = stored charge/capacitance

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23
Q

How do you determine the total capacitance of a circuit with multiple capacitors?

A

PARALLEL: C1 + C2 + Cn
SERIES: 1/Cₜₒₜₐₗ = 1/C₁ + 1/C₂ + … + 1/Cₙ

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24
Q

What factors affect the capacitance of a capacitor?

A

C = ε × A/d

Capacitance increases with larger plate area (A), smaller distance between plates (d), and higher permittivity (ε) of the dielectric material.

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25
Describe the **fire triangle** with examples from the theatre environment.
* Oxidiser (oxygen or nitrous oxide) * Fuel source (such as surgical drapes or alcohol-based preparations) * Ignition (like electrosurgical units or laser beams)
26
Describe how the frequency of ultrasound waves emitted from a probe **affects** resolution and tissue penetration.
Higher frequencies provide better resolution, but at the expense of penetration depth, making them less suitable for deep structures.
27
What **fresh gas flow** is ideal for preventing rebreathing in someone spontaneously ventilating through a Bain circuit?
100 ml/kg
28
What **technique** is used to separate enantiomers during drug development?
Simulated moving bed chromatography
29
Briefly explain how an **aneroid gauge** works.
Measures blood pressure through the mechanical expansion and contraction of bellows, which moves a pointer across a calibrated scale to indicate pressure changes.
30
What is the most accurate and reliable method of measuring **osmolality**?
Freezing point osmometer ## Footnote Determined concentration by measuring the freezing point of the solution as depression of the freezing point is directly correlated with concentration.
31
What is a **strain gauge**?
A resistor used in pressure transducers. ## Footnote A diaphragm moves as the pressure changes which changes the tension in the resistance wire, making it longer and thinner and INCREASING its resistance.
32
Which **equation** is used to determine vaporiser output from a plenum vaporiser at different ambient pressures?
% vaporiser output = % calibrated x (calibrated pressure/ambient pressure)
33
What is **Raman scattering**?
Gas analysis technique based on the Raman effect. ## Footnote Light scatters **inelastically** off gas molecules resulting in a frequency shift - this is specific to each gas. Can be affected by extreme temperatures.
34
Which **values** on a blood gas are derived rather than directly measured?
* Bicarbonate * Base Excess * Oxygen Saturation
35
What are the **main differences** between the Clark electrode and galvanic fuel cell?
**Clark Electrode (Polarographic)** * Requires external voltage and measures oxygen via an electrochemical reaction where O2 is reduced at the platinum cathode, generating a current proportional to pO2. Used in blood gas analysers. **Galvanic Fuel Cell** * Self-powered and uses spontaneous redox reaction where the anode is consumed over time. Simpler and cheaper and used in anaesthetic machines.
36
What **method of sterilisation** is best for heat- and moisture-sensitive devices?
Ethylene oxide sterilisation
37
Which **component** of the bispectral index is most crucial for the calculation of BIS score and why?
**Coherence** between high- and low-frequency EEG components. This reflects consistency of phase relationships across different EEG frequencies. In deeper anaesthesia, EEG signals become more synchronised leading to higher coherence (and lower BIS number).
38
What is the bandwidth and typical voltage range for a standard **12-lead ECG**?
**DIAGNOSTIC**: 0.05-150 Hz & 0.1-4 mV **MONITORING**: 0.5-50 Hz
39
What is the **most efficient** Mapleson circuit for spontaneous breathing?
Mapleson A Including Lack (coaxial)
40
What **fresh gas flow** is necessary to prevent rebreathing with an Ayre's T piece?
200 mL/kg/min
41
What are the **main benefits** of low flow anaesthesia via a circle system?
* Improved humidity and temperature of inspired gases (as it has passed through the respiratory tract) * Minimises consumption of volatile agents
42
State **Coulomb's law**.
Coulomb’s Law states that the electric force between two charges is inversely proportional to the square of the distance between them. In the context of **nerve stimulation**, this means the threshold current required to stimulate a nerve increases in proportion to the square of the distance between the stimulating electrode and the nerve.
43
Do you need to change the settings on a Tec 6 vaporiser at altitude?
**Yes** The Tec 6 vaporiser is designed to deliver a controlled **VOLUME PERCENT** of desflurane vapour. This will vary depending on the ambient pressure. The partial pressure of the drug is responsible for its effect. ## Footnote NOTE: Goes in 1% gradations from 1-10%, then 2% up to 18%.
44
What should be the **moisture content** of a soda lime canister?
15-20% ## Footnote NOTE: Can get up to 60 degrees celsius.
45
How **long** should an oxygen alarm sound for?
At least 7 seconds 60 dB at 1 metre
46
What **factor** is used to convert kPa to psi?
1 kPa = 0.145 psi
47
What is a **cryoprobe** and how does it work?
Surgical instrument used to **freeze** and destroy tissue. Works by rapidly cooling its tip using compressed gases (like nitrous oxide or carbon dioxide), which expand and cool (Joule-Thomson effect), freezing adjacent tissue on contact.
48
What is the **difference** between Ostwald's and Bunsen's solubility coefficients?
**Ostwald**: The ratio of the volume of a gas dissolved in a liquid to the volume of the gas at the same temperature and pressure. (Dimensionless - more commonly used) **Bunsen**: The volume of a gas, corrected to 0 °C and 1 atm, that dissolves in a unit volume of liquid at a given temperature.
49
What are **Van Der Waals' forces**?
Formed from the orbit of electrons round an atom at high speeds creating spontaneous dipole charges influencing the neighbouring dipole.
50
List the **different types of bonds** between atoms and molecules from strongest to weakest.
* Ionic * Covalent * Hydrogen * Dipole-Dipole * Van Der Waals'
51
What does '**fully saturated**' mean in the context of vaporisers?
The partial pressure of the anaesthetic vapour in the gas **equals the SVP** of the agent at a given temperature. The rest of the gas is made up of carrier gas (e.g. oxygen or air) making up the rest of the 760 mm Hg.
52
What is the **critical angle** with regards to fibreoptics?
It is the **minimum angle of incidence** at which light is completely reflected within a denser medium when it strikes the boundary with a less dense medium, enabling total internal reflection, as used in fibreoptics. ## Footnote Total internal reflection occurs when the angle of incidence is greater than the critical angle.
53
What is the **pore size** of a blood giving set filter?
200 micrometres
54
What can cause a **double waveform appearance** on pulse oximetry?
Venous congestion | (first wave is arterial pulsation, second wave is venous) ## Footnote This can happen in fluid overload, tricuspid regurgitation, right-sided heart failure and high ventilatory pressures - because these increase venous pressures and it becomes pulsatile. NOTE: The pulse oximeter will under-estimate arterial oxygen saturations because it is also reading the venous saturation.
55
How many **oscillations** after a square wave test would you see in optimally and under-damped system?
**Optimally Damped**: 2-3 **Under-damped**: > 3
56
Which **components** of the Severinghaus electrode is important to replace regularly?
Membrane covering the electrode
57
How many **litres of oxygen** does 1 L of oxygen from a VIE produce?
860 L ## Footnote NOTE: stored at -150 degrees at 7-10 bar
58
What are the **three main non-electronic methods** of measuring temperature?
* Alcohol * Mercury * Dial (bimetallic strip or bourdon gauge)
59
What **type** of blade is this?
Polio Macintosh
60
What **type** of blade is this?
Miller Straight blades with curved tips ## Footnote NOTE: used for floppy airways in paediatrics
61
What **type** of blade is this?
McCoy ## Footnote Features a hinged, lever-controlled tip on the blade that allows for elevation of the epiglottis
62
Which **parameters** are directly measured by a blood gas analyser?
* pCO₂ * pO₂ * pH
63
What **size** of soda lime granules is used?
Pass through a 4-mesh (4 openings per inch). Retained by 8-mesh (8 openings per inch). This is a granule size of 2.38 mm to 4.75 mm in diameter.
64
Write the **reaction** that takes place in soda lime.
Calcium hydroxide is the main reactant. Sodium hydroxide is a CATALYST.
65
How does a pulse oximeter ensure that it only records the **absorption of the pulsatile component** of the tissue between the light and the receiver?
Arterial pulsation **changes path length** causing changes in absorption (as per Beer-Lambert law). ## Footnote This means that it will only assess the saturations of that component (i.e. excluding tissue and venous blood).
66
What is the **speed of light**?
3 x 10^8 m/s
67
What is the **error margin** of a rotameter?
+/- 2.5%
68
Describe how a **laser beam** differs from **visible light**.
* **Collimated**: parallel rays * **Coherent**: consistent phase * **Monochromatic**: single wavelength * **High intensity**: concentrated energy
69
What is **1 dyne** equal to in SI units?
10^-5 Newtons
70
How **accurate** are thermistors and thermocouples?
+/- 0.1 degrees centigrade
71
What is the **speed** of ultrasound in tissues at 37 degrees?
1540 m/s
72
What **range** of frequencies is used by medical ultrasound?
0.5-10 MHz
73
What is a **Farad**?
Unit of capacitance ## Footnote 1 Farad is the capacitance of a capacitor that stores one coulomb of charge when one volt is applied across it.
74
How **fast** does the fluid at the centre of the column in laminar flow compare to the average speed of the entire column?
Twice the average speed.
75
Outline a **defibrillator circuit**.
1. Step-up transformer increases 240 to 5000 V 2. Capacitor needs DC to charge so rectifier (diode) converts AC to DC 3. Switch charges and discharges capacitor 4. Inductor smooths the current delivered to the defibrillator pads ## Footnote NOTE: A smoother discharge means that heart is depolarised more effectively and safely, it reduces tissue damage and minimises electrical stress on the device.
76
State **Raoult's law**.
The partial vapour pressure of a component in a solution equals the vapour pressure of the pure component multiplied by its mole fraction in the solution. ## Footnote **EXAMPLE** In a 1:1 mole ratio mixture of ethanol (SVP 44 mmHg) and water (SVP 24 mmHg), the total vapour pressure = (0.5 × 44) + (0.5 × 24) = 34 mmHg.
77
What **voltage** is applied across a Clark electrode?
0.6-0.7 V
78
At what **elevation** will atmospheric pressure reach 75%, 50%, and 25% of sea level?
* 75%: 2500 m * 50%: 5500 m * 25%: 11,000 m
79
What is the **formula** that links capacitance to the factors that determine it?
Permittivity = how easily it allows an electric field to pass through it.
80
What is a **dielectric**?
Insulating material that, when placed in an electric field, becomes polarised, allowing it to **support the field** and store electrical energy without conducting current. ## Footnote Used in capacitors.
81
What are the **sizes** of the connectors on endotracheal tubes and catheter mounts?
ETT: 15 mm Catheter Mount: 22 mm
82
What **disease state** can lead to inaccuracies in the oesophageal Doppler readings?
Aortic arch pathology ## Footnote Because the Doppler relies on the assumption that 70% of cardiac output enters the descending aorta. It also assumes that the cross-section of the descending aorta can be assumed based on demographic data.
83
What is the **pore size** of the bacterial filter in an HMEF?
0.2 microns
84
How does the VIE **adjust** at times of high usage compared to low usage?
**HIGH USAGE** (also cold weather): decrease in oxygen temperature and pressure, at 1000 kPa, the pressure raising valve opens allowing liquid oxygen to shunt through a pressure-raising vaporiser and allow environmental heat to enter. **LOW USAGE** (hot weather): temperature of liquid oxygen increases and pressure increases, blow off valve opens to allow vapour into the environment.
85
What are the **main features** of a pulmonary artery catheter?
* 110 cm with 5 lumens * Proximal lumen is 30 cm from tip and sits in right atrium * Balloon at tip is filled with 1.5 mL of air and floated through the circulation whilst observing the pressure trace * Thermistor 3.7 cm from tip
86
What does this **symbol** represent?
Thermistor
87
What is the **purpose** of the heat sink effect of the casing of plenum vaporisers?
Transfers energy to the volatile agent to prevent it from cooling down due to latent heat of vaporisation. ## Footnote This maintains a stable SVP and is particularly important with high fresh gas flows.
88
What is the **Doppler** equation?
The Doppler equation describes the change in frequency or wavelength of a wave in relation to an observer moving relative to the wave source. ## Footnote It is commonly used in physics and astronomy to explain phenomena such as the redshift and blueshift of light from stars and galaxies.
89
What is the volume of oxygen within a **full size F cylinder**?
1360 L
90
What is the volume of oxygen within a **full size G cylinder**?
3400 L
91
What is the volume of oxygen within a **full size J cylinder**?
6800 L
92
What **measures** can be taken to prolong the duration of cylinder oxygen supply in the event of mains oxygen failure?
* Use circle system * Lowest possible FGF * Lowest possible FiO2 * Check FiO2 alarms
93
Which measure on a **blood gas machine** is derived?
Bicarbonate ## Footnote It is measured based on the pCO2 and the Henderson-Hasselbalch equation.
94
What is the frequency used by **ultrasound probes**?
1-15 MHz ## Footnote NOTE: Speed of sound in tissues at body temperature is 1540 m/s.
95
What is the **peak absorbance wavelength** of infrared radiation for anaesthetic gases, nitrous oxide, and carbon dioxide?
* **Anaesthetic Gases**: 8-9 µm * **Nitrous Oxide**: 4.6 µm * **Carbon Dioxide**: 4.3 µm
96
In a galvanic fuel cell, which **type of reaction** takes place at each electrode?
**Lead Anode**: electrons are lost in an oxidation reaction **Gold Cathode**: electrons are gained in a reduction reaction
97
Outline the **NAPSE coding** of cardiac pacemakers.
* **Position I**: chamber(s) paced – V (ventricle), A (atrium), D (ventricle and atrium), O (none). * **Position II**: chamber(s) sensed – V (ventricle), A (atrium), D (ventricle and atrium), O (none). * **Position III**: mode of response – T (triggered), I (inhibited), D (triggered or inhibited), O (none). * **Position IV**: programmable functions – R (rate modulated), O (none). * **Position V**: multi-site pacing – O (none), A (atria), V (ventricles), D (dual).
98
What are the **8 methods** of classifying a ventilator?
* **Method of cycling**: volume, time, pressure * **Inspiratory phase gas control**: volume, pressure * **Source of power**: electric, pneumatic * **Suitability of use**: operating theatre, ICU * **Paediatric use**: yes, no * **Method of operation:** pressure generator, flow generator * **Sophistication**: SIMV, PS, CPAP etc. * **Function**: minute volume divider, bag squeezer, intermittent blower
99
What is the **major determinant** of the diameter of a fibreoptic endoscope?
Size of the main working channel
100
What is a **Wheatstone bridge**?
* Pair of voltage dividers. * Designed to measure an unknown resistance by balancing two limbs of a bridge circuit so that the voltage between them is 0. ## Footnote Has 2 fixed resistors (R1 and R2), a variable resistor (R3) and the resistance to be measured (Rx). To produce a voltage of 0, R3:R1 and Rx:R2 must be the same. R3 is altered until the voltmeter reads 0.
101
Define a **Farad** with regards to capacitors.
A capacitor with capacitance of 1 Farad will store 1 Coulomb of charge when 1 Volt (not Amp) is applied across it.
102
Why is a **Newton valve** useful when using a Penlon Nuffield 200 Ventilator to ventilate a child?
Newton valve affords the user **greater control over tidal volume**, and thus reduces the risk of volutrauma in paediatric patients. ## Footnote It can deliver up to 300 mL of tidal volume.
103
What are the **pin index configurations** for oxygen, air, carbon dioxide, nitrous oxide, and entonox?
* **Oxygen**: 2, 5 * **Medical Air**: 1, 5 * **Carbon Dioxide**: 1, 6 * **Nitrous Oxide**: 3, 5 * **Entonox**: 7
104
What are the **differences** between pencil point and cutting needles?
A **pencil-point needle** (e.g., Whitacre or Sprotte) has a rounded, non-cutting tip with a side hole for drug delivery. It spreads dural fibers rather than cutting them, reducing the risk of post-dural puncture headache (PDPH). A **cutting needle** (e.g., Quincke) has a sharp, beveled tip that slices through tissues, making dural puncture easier but increasing the risk of PDPH due to greater dural trauma.
105
What **humidity** can be achieved with an HMEF?
HMEFs can achieve a relative humidity of **60-70%**. At 37ºc the maximum absolute humidity of air is 44 g/m³. ## Footnote 60-70% of 44 g/m³ is 26.4 – 30.8 g/m³
106
Which **types of gases** can be detected by infrared gas absorption spectroscopy?
When a gas contains two or more dissimilar atoms. The bond between the atoms can absorb energy at specific wavelengths leading to absorption spectra that can be used to identify and quantify the gas. ## Footnote E.g. N2O can be detected but not O2.
107
What is the **Seebeck effect**?
When two conductors made from dissimilar materials are joined together, a potential difference is produced at the point of contact, the magnitude of which depends on the temperature.
108
How does a **thermocouple** work?
At the junction of two dissimilar metals, a voltage will be produced in **direct proportion to the temperature difference between two such junctions**. Typically copper and constantan are the metals used. The response is nearly linear and passes through the origin as a temperature difference of 0 produces 0 output voltage. ## Footnote Uses the Seebeck effect.
109
What is the **difference** between relative and absolute humidity?
**Relative humidity** refers to the amount of water vapour in a gas sample relative to the mass if the gas sample was fully saturated. It is measured in %. **Absolute humidity** refers to the total mass of water within a given volume of gas, and is measured in g/m3.
110
Which device is used to measure **absolute humidity**?
Mass spectrometer
111
What is the **order** of components in a scavenging system?
Designed for occupational safety - all gases are eventually vented into the atmosphere. * Collecting system * Transfer system * Interface (allows pressure to be vented so that it is not transmitted to the patient) * Disposal system
112
What is the **difference** between absolute and relative humidity?
The **absolute humidity** is the mass of water vapour in a given volume of gas at a given temperature and pressure and is often expressed in g/m³. The **relative humidity** is the ratio of the actual mass of water vapour compared to the maximum amount of water vapour the gas could contain at the same temperature and pressure.
113
What is the **dew point**?
The temperature to which a given volume of gas must be cooled for water vapour to condense. This occurs when the **relative humidity is 100%**. If air has a lower humidity therefore a greater temperature drop is required to reach the dew point.
114
What is the maximum possible absolute humidity at **body temperature**?
44 g/m³
115
What **factors** affect the angle of refraction when light passes into a different medium?
* Angle of incident ray * Refractive index of air * Refractive index of material * Speed of light in material
116
How **often** should a galvanic fuel cell be calibrated?
Calibrate daily using a two point method with 21% (room air) and 100% oxygen.
117
What are the **two considerations** when deciding where to place the neutral electrode in monopolar diathermy?
**Good muscle bulk** and **blood supply** means better conductivity and less heat generation. ## Footnote Proximal to operating site means lower chance of current division, reduced impedance and less power needed.
118
What are the **main benefits** of a high pass filter in an ECG?
Reduces respiratory and body movement artefacts. ## Footnote NOTE: High-pass is the same as low-frequency because signals ABOVE a certain frequency (i.e. 0.5 Hz) are allowed to pass.
119
What is the equation for **inductance**?
**H = Wb/A** ## Footnote H = Henry (unit of inductance) Wb = Weber A = Ampere NOTE: To get a value for self-inductance, you need to multiply by the number of turns in the coil.
120
What is a **residual current device**?
Sensitive piece of equipment that monitors the current flowing through the live and neutral wires and, if there is any discrepancy, it will break the circuit. ## Footnote This can happen with even very small discrepancies.
121
What is a **current-operated earth leakage circuit breaker**?
Breaks a circuit when it detects small leakage currents. ## Footnote Live and neutral wires are wound round a transformer with the same number of windings. There is a third winding attached to a circuit breaker. When there is a difference between the live and neutral wires, it produces a magnetic field which induces a current in the third winding which breaks the circuit.
122
What is **aliasing** in the context of Doppler ultrasound?
Sampling error where an insufficient frequency of pulses relative to the velocity of blood flow being measured results in the system not being able to determine the direction of blood flow correctly.
123
What **assumptions** just oesophageal Doppler cardiac output monitoring rely upon?
* Aortic cross-section provided by normogram * Probe position unchanged with fixed angle between probe and aorta * Flow is laminar * 70% of LV output going into descending aorta
124
What are the **different components** of a cell salvage system?
* **SUCTION**: collects blood using heparin or citrate to prevent clotting * **RESERVOIR**: stores and roughly filters blood, removing large clots * **CENTRIFUGE**: separates red cell from plasma and contaminants * **WASHING**: isotonic saline removes free haemoglobin, activated clotting factors and anticoagulants * **FILTRATION**: leukocyte depletion filter to remove white cells and microaggregates * **REINFUSION BAG**: stores concentrated clean red cells for transfusion
125
What is the **difference** between the Lack and Bain circuits?
Both are co-axial. **Lack** behaves like a Mapleson A (FGF on outside). **Bain** behaves like Mapleson D (FGF on inside). Can be very long without much issue because FGF delivered right to patient.
126
What are the **benefits** of a high-pass (low frequency) vs low-pass (high frequency) filter on an ECG machine?
**High Pass** (low frequency): better assessment of ST segment, P wave and T wave . **Low Pass** (high frequency): good for QRS and tachyarrhythmias.
127
What is the **purpose** of having a differential amplifier in an ECG circuit?
Measures the potential difference between two leads and eliminated inputs that are common (common mode rejection). This helps remove background noise.
128
What is the **Kety-Schmidt method**?
* Technique to measure regional blood flow (usually cerebral). * Inert, diffusible tracer gas like nitrous oxide is used. * Blood and tissue tracer concentrations are measured over time and flow is calculated based on tracer uptake.
129
What is the **optimal internal diameter** of a central venous catheter?
1.3-1.63 mm | (14-16 G)
130
At what **level** should the transducer be set for central venous pressure measurement?
Intersection of 4th intercostal space and mid-axillary line (this is where the right atrium is).
131
What is a **refractometer**?
* Method of measuring the concentration of an inhalational agent. * Measures the extent to which light is bent when it moves from air into a sample gas.
132
What are the **three main safety features** of the pipeline gas supply between the wall and the anaesthetic machine?
* **Schrader Sockets**: unique diameter index collar matches the relevant socket * Flexible, kink-proof **colour-coded pipe** (blue for nitrous, white for oxygen, black for air) * **Non-Interchangeable Screw Thread**: nut and probe with unique profile for each gas, unidirectional valve ## Footnote NOTE: Pin index is for the cylinders that are mounted on the back of the machine.
133
Describe how a **null deflection paramagnetic oxygen analyser** works.
Dumbbell of nitrogen is aligned perpendicular to a magnetic field and balanced on a suspending filament. Oxygen will be attracted to the magnetic field causing a deflection in the dumbbell. Photocells are used to control a variable current that induces a magnetic field that exactly offsets movement due to oxygen - the current is used to calculate oxygen concentration.
134
What is the **difference** between active and passive transducers?
**ACTIVE**: generate electric current or voltage directly in response to environmental stimulation (e.g. thermocouple) **PASSIVE**: change in passive electrical quantity such as resistance, capacitance or inductance (e.g. strain gauge, thermistor)
135
What are **anaesthetic gas cylinders** made of?
Steel alloy (manganese molybdenum steel, chromium molybdenum steel or nickel chromium molybdenum steel).
136
What is the **filling ratio** of a cylinder?
WEIGHT of cylinder contents divided by WEIGHT of water it could hold.
137
What **microshock current** can cause VF for a device placed within the body?
100 microamps
138
In which **ECG leads** are P waves most easily seen?
II, III and aVF V1
139
# Define: a metal
An element that tends to lose electrons to form positive ions and has characteristic properties such as high electric and thermal conductivity, malleability, ductility and a shiny appearance due to free-moving electrons in a metallic bond.
140
# Define: heat
Thermal energy that flows from one body in contact with another when they are at different temperatures.
141
# Define: temperature
Mean kinetic energy of molecules within a body.
142
# Define: conduction | (with regards to heat transfer)
Occurs via direct collisions between atoms and molecules of warmer and cooler regions and the resultant transfer of kinetic energy. ## Footnote Unit of conductivity is W/K/m.
143
# Define: convection | (with regards to heat transfer)
Transfer of heat from a body by the liquid or gas that surrounds it. ## Footnote Passive: still air Active: moving air (e.g. bear hugger)
144
# Define: radiation | (with regards to heat transfer)
Hot bodies emit thermal energy in the form of electromagnetic radiation resulting in heat transfer.
145
State **Stefan-Boltzmann Law**.
Radiation energy per unit time from a black body is proportional to the **fourth power of the absolute temperature**.
146
# Define: emissivity
Is a dimensionless quantity which quantifies the ability of a body to radiate heat. ## Footnote This is expressed as a comparison to a perfect black body surface at the same temperature (a black body has a value of 1).
147
# Define: a black body
A body that absorbs all radiation that falls upon it.
148
State the **routes of heat loss** from the body and their relative proportions.
* Radiation: 40% * Convection: 30% * Evaporation: 20% * Respiration: 10% ## Footnote NOTE: Average emission is 50 watts per square metre.
149
State the **first law of thermodynamics**.
Energy cannot be created or destroyed, only transformed from one form to another. ΔU = Q − W ## Footnote ΔU = change in internal energy of a system Q = heat added to the system W = work done by the system
150
State the **second law of thermodynamics**.
In any natural thermodynamic process, the total entropy of a system and its surroundings always increases. ΔS = ΔQ/T ## Footnote ΔS: change in entropy ΔQ: heat entering the system T: temperature
151
State the **third law of thermodynamics**.
As the temperature of a system approaches absolute zero (0 K), the entropy of a perfect crystalline substance approaches zero. ## Footnote The temperature absolute zero is unattainable.
152
# Define: adiabatic expansion
Thermodynamic process in which a gas expands without exchanging heat with its surroundings. Any change in internal energy comes solely from work done by the gas. It usually leads to a drop in temperature, since the gas does work but receives no heat to compensate.
153
Describe the **Joule-Thompson effect**.
A gas changes temperature when it moves from a higher pressure to a lower pressure and for most gases, they cool.
154
# Define: a wave
Series of repeating disturbances that propagates in space and time. ## Footnote **Longitudinal Waves**: oscillations occurring in the direction of travel (e.g., sound waves) **Transverse Waves**: oscillations perpendicular to the direction of travel (e.g., Mexican wave)
155
State the equation that gives the **velocity of a wave**.
Velocity = Frequency x Wavelength
156
Which sound wavelengths and frequencies can be heard by the **human ear**?
20-20,000 Hz 170 mm to 0.17 mm
157
How does the speed of light **differ** from the speed of sound in terms of the densities of the media it travels through?
Speed of light travels faster through less dense materials. Sound travels faster through more dense material.
158
# Define: simple harmonic motion
Characterised by periodic oscillation about the equilibrium position and each oscillation is one cycle. The acceleration of an object is proportional and in opposition to its displacement from the equilibrium position. ## Footnote Example: child on a swing
159
# Define: resonance
When the system oscillates with maximum amplitude. ## Footnote This occurs when the external driving frequency equals the natural frequency of the material.
160
# Define: natural frequency
Frequency at which a system oscillates when displaced from its equilibrium position and allowed to vibrate freely without any external forces acting on it.
161
# Define: damping
Tendency to resist oscillation.
162
What is a **harmonic series**?
Most oscillators resonate at multiple frequencies. The lowest is the natural frequency, and integer multiples of this are called harmonics.
163
What is **Fourier analysis**?
Mathematical model for analysing a periodic waveform to find its component frequencies. It will plot a spectrum of frequencies (amplitude against frequency). In the context of invasive blood pressure monitoring: enables detection of oscillatory patterns, filtering of noise, and precise assessment of heart rate and waveform features.
164
What is the **radiant flux** of a light source?
Number of joules of energy emitted each second - expressed in watts.
165
What is the intensity or irradiance of a **light source**?
Describes how much energy falls on a surface and is measured in watts per square metre.
166
Which **equation** describes the intensity of light at a distance of R from a source?
**I = P/4πr²** ## Footnote P = total power output from light (watts)
167
Describe how a **simple manometer** works.
Measures pressure in a gas by vertical displacement of a liquid in a tube If the density of the liquid is known, the difference in column height can be used to calculate the hydrostatic pressure of the displaced column which is equal to the gas pressure. ## Footnote Derivation P = F/A P = mg/A P = ((Density x Area x Height) x Gravity)/Area Gauge Pressure = Density x Gravity x Height
168
What is a **Bourdon gauge**?
Consists of a C-shaped hollow spring-like tube that extends outwards at the sealed end when pressure rises in the tube. The expansion and contraction is relayed to a pointer that indicates the pressure on a calibrated dial.
169
What is a **barometer** and how does it work?
It measures absolute atmospheric pressure. A sealed, liquid-filled tube is inverted into a reservoir (Torricellian vacuum) Atmospheric pressure pushes on the reservoir, balancing the column of liquid. The height of the liquid column is proportional to atmospheric pressure. ## Footnote NOTE: Mercury is used due to its high density, keeping the column height manageable.
170
What is a **pressure relief valve**?
Relieves pressure beyond a specified limit and re-closes upon return to the normal pressure range.
171
Describe how an **adjustable pressure limiting valve** works.
Turning a screw raises or lowers the spring and diaphragm. When lowered, more pressure is required to raise the diaphragm enough for gas to escape through the apertures. The diaphragm is pushed upwards and reaches a point where the gas can escape. The adjustable pressure limit valve allows the blow-off pressure to be adjusted by turning a screw that raises or lowers the spring and diaphragm. When the spring is lowered, the spring must be compressed further so more pressure is needed to raise the diaphragm enough for the gas to escape.
172
Describe how a **pressure regulator valve** works.
Used to supply a flow of gas to an outlet (e.g. facemask) at a much lower pressure than the supply (e.g. cylinder). Gas flows into a chamber via an aperture around a piston If the chamber pressure gets too high, the diaphragm and piston rise to narrow the aperture. This restricts gas flow into the chamber, thereby reducing outflow pressure.
173
What is the **siphon effect**?
Physical phenomenon where a liquid is drawn from a higher container to a lower one through a tube, with the liquid flow maintained by gravity and hydrostatic pressure differences, once the tube is initially filled.
174
Why is a vent **necessary** for infusions running from glass vials?
The subatmospheric pressure created in the bottle as liquid flows from the bottle to the vein would mean that the pressure will equilibrate with the pressure in the vein, thereby stopping drug delivery. A vent in the bottle enables air to replace the liquid so the pressure in the bottle remains atmospheric.
175
Why might an elevated syringe driver empty **faster**?
If a syringe driver is placed at a significant height above the patient, the weight of the column of fluid (hydrostatic pressure) could overcome the friction between a plunger and the barrel, thereby making the syringe empty faster.
176
What is an **oscillometer**?
Instrument for measuring the changes in pulsations in the arteries, especially of the extremities. The cuff is inflated and slowly deflated through a valve whilst a sensor monitors the cuff pressure and the small oscillations which begin as soon as cuff pressure drop below the systolic. Max amplitude occurs when the cuff pressure is equal to the mean pressure.
177
Describe the **Penaz volume clamp technique**.
Monitors arterial blood volume via light absorption (photoplethysmography). Increased blood volume → more light absorbed → less detected. A cuff inflates until blood volume is constant—this occurs at mean arterial pressure. A feedback system adjusts cuff pressure in real time to maintain constant arterial volume, approximating MAP. ## Footnote NOTE: Only works in vasodilated patients
178
How does an **invasive blood pressure monitor** work?
Uses a pressure transducer with strain gauges in a Wheatstone bridge to detect small pressure changes. A fluid-filled catheter (saline-heparin) transmits arterial pressure to the transducer. Sensor is placed at cannula level and zeroed to atmospheric pressure by exposing it briefly to air. Continuous saline flush (3–5 mL/hr) prevents clotting and maintains patency.
179
How does **underdamping** affect the blood pressure result in invasive blood pressure monitoring?
Systolic: overestimated Diastolic: underestimated
180
How does **overdamping** affect the blood pressure result in invasive blood pressure monitoring?
Under-estimates systolic Over-estimates diastolic
181
List some **causes** of over-damping of arterial line trace.
* Long catheter * Narrow catheter * Air bubble (compressible meaning that a lot of the pressure change is absorbed by the bubble and not transmitted to the transducer)
182
Explain how **clouds** form.
Sun heats water → evaporation increases water vapor Water vapor displaces heavier gases → air becomes less dense and rises Rising air expands and cools (adiabatic expansion) → condensation occurs Condensation forms clouds and leads to rise in air density
183
What is **absolute humidity**?
Mass of water molecules per unit volume (grams per metre cubed).
184
Explain how a **wet and dry bulb hygrometer** works.
Uses two thermometers: a dry bulb to measure ambient temperature, and a wet bulb wrapped in a water-saturated wick. The rate of evaporation from wick depends on relative humidity of surrounding air. Evaporation from wick causes a drop in temperature on the wet bulb. Temperature difference correlates to relative humidity.
185
Explain how a **hair tension hygrometer** works.
Hair contains cytokeratin molecules linked by disulphide bridges and hydrogen bonds. H bonds absorb moisture from the air, causing the hair to lengthen. The degree of lengthening depends on relative humidity and can be calibrated to give a humidity reading.
186
Explain how a **Regnault's hygrometer** works.
Air is passed through ether in a silver tube, causing it to evaporate and cool the tube via latent heat loss. Condensation on the tube’s surface marks the dew point temperature. Modern versions use a chilled mirror and electronic sensors to detect condensation.
187
What is the **absolute humidity** of alveolar air?
44 g/m3 Gives a partial pressure of around 6.3 kPa
188
What is a **heat and moisture exchanger** made of?
Calcium chloride or silica
189
Explain how an **HME** works.
Exhaled warm, moist air condenses on the material, releasing latent heat and warming it. On the next inhalation, dry gas passes over the warm, moist material, becoming warmed and humidified. Approx. 80% efficient in conserving heat and moisture. A 0.2 µm filter can be added to block bacteria/viruses, preventing circuit contamination.
190
How much **dead space and resistance** is added to the breathing circuit by an HME?
100 mL in adults Up to 2 cm H2O resistance ## Footnote NOTE: It can get blocked with secretions which increases the resistance.
191
What are the **two types** of water bath humidifiers?
**Active**: Use heating elements and thermostats to reach up to 100% efficiency, but are bulky—used mainly for long-term ventilation. **Passive**: Bubble inspired gas through water to saturate it with humidity.
192
Why is temperature control **important** for active water bath humidifiers?
Water temperature limits humidity; evaporation cools the bath (latent heat loss). ## Footnote Active systems maintain temperature (typically 40–60°C) with a thermostat. 40°C: Less scald risk, more microbial growth. 60°C: More scald risk, lower infection risk.
193
Describe how the **size** of the droplets generated by a nebuliser relates to the pharmacological effect.
* < 3 µm: enter the alveoli and THERAPEUTICALLY BENEFICIAL * 1 µm = ideal * 5-10 µm: deposit in the upper airways
194
How does a **jet-driven nebuliser** work?
High-pressure gas flows over a capillary tube immersed in fluid. Gas passes through a small orifice, creating negative pressure via the Bernoulli principle. This draws fluid up and converts it into an aerosol mist.
195
How does an **ultrasound-driven nebuliser** work?
A ceramic piezoelectric transducer converts electrical energy into mechanical vibrations (~1.5 MHz). Vibrations pass through water to a flexible diaphragm. The diaphragm vibrates the solution, breaking it into fine aerosol particles. The particle size is more consistent.
196
# Define: flow
The movement of a gas or liquid through a tube or other system (volume passing a point per unit time).
197
# Define: laminar flow
Smooth, orderly movement of fluid in parallel layers.
198
How does **Ohm's law** apply to laminar flow?
In laminar flow, flow is directly proportional to driving pressure. Q = ΔP/R
199
What is **Poiseuille's** equation?
A mathematical formula that describes the **flow rate of a fluid** through a cylindrical pipe, given by the equation: **Q = (πΔPr^4) / (8ηL)** ## Footnote This equation illustrates how flow rate is influenced by pressure difference, pipe radius, fluid viscosity, and length of the pipe.
200
# Define: turbulent flow
A chaotic, irregular fluid motion characterised by swirling eddies and vortices, where layers of fluid mix unpredictably.
201
State the formula for **Reynolds number**.
Re = (Velocity x Radius x Density)/Viscosity ## Footnote Interpretation < 2000 = Laminar 2000-4000 = Transitional > 4000 = Turbulent
202
Describe the **relationship** between driving pressure and flow rate in turbulent flow.
Q ∝ √ΔP Q² ∝ ΔP The gradient is resistance which increases with flow rate
203
# Define: the Bernoulli principle
Fluid moving rapidly (e.g. through a constriction) exerts less pressure than a static fluid.
204
Explain the **theory** behind the Bernoulli principle.
As velocity increases at a constriction, the kinetic energy increases and, for the total energy within the system to remain constant, the potential energy must decrease. The potential energy of a gas is proportional to the pressure it exerts, so the pressure exerted on the walls of the tube will decrease with increased velocity.
205
What is the **Venturi effect**?
If the Bernoulli principle is used to create an area at subatmospheric pressure, it will **entrain air**.
206
What determines the percentage of oxygen delivered by a **Venturi device**?
Rate of entrainment (determined by the size of the holes) Rate of flow of oxygen (to a lesser extent) Entrainment Ratio = Entrained Flow/Driving Flow
207
# Define: the Coanda effect
A fluid or gas stream will hug a convex contour when directed at a tangent to that surface.
208
Why does the Coanda effect **happen**?
A fast-moving fluid jet generates a region of lower pressure around it, entraining surrounding fluid into the stream. When the jet encounters a nearby surface, entrainment is reduced on the side facing the surface, leading to a local drop in pressure. This pressure differential causes the jet to be drawn toward and follow the contour of the adjacent surface.
209
Describe how a **variable orifice flowmeter** works.
* It is a tapered vertical tube with a bobbin that rises as gas flow increases. * The bobbin equilibrates when the upward force of gas balances its weight. * The conical shape allows more air around the bobbin at higher gas flows. * It is calibrated for specific gases due to viscosity/density.
210
How can lung volume be **deduced** from respiratory flow rates?
It is the time-integral of the flow rate. ## Footnote I.e. flow is volume passing a certain point per unit time, the area under the curve will be the lung volume
211
How can a volume-time curve be **converted** into a flow rate-time curve?
It is the differential of the volume-time curve.
212
Explain how a **rotating vane flowmeter** works.
Measures gas flow using a small turbine that spins with the flow. Interruptions of a light beam by the turbine generate a voltage proportional to flow rate. Most accurate at low respiratory flows due to turbine inertia.
213
Explain how a **pneumotachometer** works.
It measures airflow by detecting the pressure difference across a fine mesh in a tube (fixed resistance). This **pressure difference**, sensed by pressure sensors, is proportional to flow rate (per Ohm’s law) under laminar conditions. A widened tube ensures laminar flow by reducing velocity and the Reynolds number.
214
How does a **pitot tube flowmeter** work?
Measures flow by comparing pressure in two sealed tubes—one facing into the airflow and one facing away. The flow-facing tube compresses air, creating a pressure increase. The pressure difference reflects the square of the flow velocity (kinetic energy = 1/2(mv^2)), which is assumed proportional to flow rate. Unlike pneumotachometers, they use no flow resistor.
215
Explain how a **Wright peak flow meter** works.
It measures peak expiratory flow by using exhaled air to push a diaphragm against a spring. As the diaphragm moves, it opens a narrow slot for air to escape, reducing pressure. A sliding marker is pushed by the diaphragm and stops when the spring force balances the airflow pressure, indicating the peak flow rate.
216
Explain how a **Benedict-Roth spirometer** works.
It measures lung volume by collecting exhaled gas in a sealed, movable bell chamber. As air enters, the bell rises or falls, with its displacement proportional to the volume of air exhaled. A water seal ensures airtight movement, and the motion is recorded—traditionally on a rotating drum. It may underestimate volume due to air cooling and condensation inside the chamber.
217
Describe the **features** of an ideal gas.
* Molecules are so far apart that there is no attraction between them. * Volume of the molecules themselves is negligible. * Molecules are in random motion, obeying Newton's laws of motion.
218
What is **standard temperature and pressure** when discussing gases?
Temperature of 273.15 K (0 degrees) Atmospheric pressure of 101.3 kPa = 760 mm Hg
219
State **Avogadro's law**.
Equal volumes of gases, at the same temperature and pressure, contain the same number of molecules.
220
# Define: one mole
A unit of measurement that is the amount of a pure substance containing the same number of molecules as there are atoms in exactly 12 grams of carbon-12 (i.e., 6.022 x 10^23).
221
What is **Avogadro's constant**?
Quantifies how many molecules make up one mole. | (6.02 x 10^23 per mole)
222
What **volume** does 1 mole of an ideal gas occupy at STP?
22.4 litres
223
State **Dalton's law**.
For a gas, the total pressure is simply all the partial pressures added together.
224
What is the **rough partial pressure** of water in ambient room air?
1.3 kPa
225
State **Boyle's law** | (First Ideal Gas Law)
The volume of a gas is inversely proportional to its pressure at a fixed temperature. P α 1/V
226
State **Charles' law** | (Second Ideal Gas Law)
At a given pressure, the absolute temperature (in kelvin) is directly proportional to the volume of the gas.
227
State **Gay-Lussac law** | (Third Ideal Gas Law)
The pressure of a gas is directly proportional to its temperature within a fixed volume.